Frequency of germline pathogenic variants in breast cancer predisposing genes in a national cohort of young women with breast cancer

by Janelle Cobb | Oct 7, 2026 | PUBLICATIONS

Background: The objective of the study was to evaluate the prevalence of pathogenic variants in 18 cancer predisposition genes in a national cohort of women with breast cancer diagnosed at age 40 or younger. Methods: Women with breast cancer at age ≤40 years were...

ASO Visual Abstract: Surgeon and Patient Reports of Fertility Preservation Referral and Uptake in a Prospective Pan-Canadian Study of Young Women with Breast Cancer

by Janelle Cobb | Oct 7, 2026 | PUBLICATIONS

Carmona CA, Yee S, Seminsky M, Glass K, Foong S, Lipson E, Baxter NN, Friedenreich CM, Metcalfe K, Isherwood S, Akbari MR, Narod S, Quan ML, Warner E. ASO Visual Abstract: Surgeon and Patient Reports of Fertility Preservation Referral and Uptake in a Prospective...

Risk factors for psychological morbidity and the protective role of coping self-efficacy in young women with breast cancer early in diagnosis: a national multicentre cohort study

by Janelle Cobb | Oct 7, 2026 | PUBLICATIONS

Purpose: Young women with breast cancer (YWBC) are an understudied population and there are limited data on risk factors for psychological morbidity early in diagnosis. We examined psychological morbidity (anxiety, depression, stress symptoms), well-being and...

Surgeon and Patient Reports of Fertility Preservation Referral and Uptake in a Prospective, Pan-Canadian Study of Young Women with Breast Cancer

by Janelle Cobb | Oct 7, 2026 | PUBLICATIONS

Background: Prompt referral by their surgeon enables fertility preservation (FP) by young women with breast cancer (YWBC) without treatment delay. Following a FP knowledge intervention, we evaluated surgeon and patient reports of fertility discussion, FP referral...

A pan-Canadian prospective study of young women with breast cancer: the rationale and protocol design for the RUBY study

by Janelle Cobb | Oct 7, 2026 | PUBLICATIONS

Introduction: The understanding of the biology and epidemiology of, and the optimal therapeutic strategies for, breast cancer (bca) in younger women is limited. We present the rationale, design, and initial recruitment of Reducing the Burden of Breast Cancer in Young...

Oncofertility Knowledge, Attitudes, and Practices of Canadian Breast Surgeons

by Janelle Cobb | Oct 7, 2026 | PUBLICATIONS

BACKGROUND: Guidelines recommend that oncologists discuss treatment-related fertility issues with young cancer patients as early as possible after diagnosis and, if appropriate, expedite referral for fertility preservation (FP). This study sought to determine the...